Yes, in time, the wood fibers will change their alignment according to who plays it regularly. School harps that are regularly played by many people lose their focus. My teacher, Frances Miller, told me that, and every summer, she would take one or more university harps to her cabin, and play scales and exercises on them until the sound was revived. My own harp has changed greatly over the years. You can control the sound as long as the wood is able to be cooperative. And even when a harp has a new owner, it will retain some of the signature of the previous owner.